![]() However, in reptiles and other exotic species, the tablet formulations might not be as palatable, easy to administer and can potentially cause oral ulcerations. In the USA, enrofloxacin is commercially available in the injectable form and tablets approved by the FDA for dogs and cats (1). ![]() But, on occasions, some patients may develop topical side effects to the medication. In my experience, this antimicrobial is a great option for fast healing of skin wounds in reptile patients. After the second injection, lesions started to visually disappear and no side effects were reported. After discussing with the client every aspect of environmental modification to prevent the problem from recurring, I recommended enrofloxacin intramuscular injections in the first (cranial) 1/3 of the python’s body at 5 mg/kg every 3 days (q 36 hours) until lesions improved. Other than the presented symptoms, the python was behaving and eating normally. The patient also presented with upper respiratory congestion, which was noticed during the physical examination as a harsh upper nasal noise. For example, this python (see figure 1) has facial lesions from self-induced trauma after some components of the enclosure materials were changed from plastic to wood. In reptiles, it is mostly used in upper respiratory infections, wounds, abscesses and critically ill individuals. In most of our patients, it is metabolized to ciprofloxacin, which may contribute to additional antibacterial effects. (4) The drug acts by inhibiting DNA and RNA synthesis within the pathogen. Baytril 22.Compounded enrofloxacin in reptile speciesĮnrofloxacin is a synthetic antimicrobial prescribed in disease states involving susceptible bacteria like Staphylococcus, Proteus, Escherichia coli, Pasteurella, Klebsiella and Pseudomonas aeruginosa.Enrofloxacin 100mg/ml injectable suspension.Treatment of urinary tract infections or pyelonephritis where culture/susceptibility demonstrates susceptibility to lower tier antimicrobials.įormulations Available within the OSU Pharmacy.Treatment of Gram-positive infections without known susceptibility results.Anaerobic infections, including empiric treatment of cat bite abscesses.coli (granulomatous colitis) or Campylobacter spp. Treatment of enteric infections associated with Gram-negative organisms such as E.Treatment of osteomyelitis or septic arthritis, with or without the addition of rifampin.Treatment of respiratory tract infections, including pneumonia.Also useful for treatment of otitis media/interna. Treatment of infected wounds or deep pyoderma associated with culture-confirmed susceptible organisms, or empiric treatment of suspected Pseudomonas aeruginosa (e.g.Treatment of complicated or culture/susceptibility-confirmed resistant urinary tract infections, pyelonephritis, and prostatitis.Excretion is primarily in bile, with a component of active drug in urine. Distribution is wide enrofloxacin crosses the blood-brain barrier and can enter abscesses, the prostate, and bone. It is also not effective against anaerobes. and may not be effective against some Streptococcus spp. ![]() Gram-positive coverage is limited and often includes Staphylococcus spp., but enrofloxacin is not effective against Enterococcus spp. Selected Antimicrobial Information – Companion AnimalĮnrofloxacin Restriction StatusĢ.5mg/kg PO, IV or SQ q12h or 5mg/kg PO, IV, or SQ q24h for no more than 30d (ideally, 7-14d)ĥ-10mg/kg PO, IV or SQ q24h for no more than 30d (high end of dose range preferred for Pseudomonas soft tissue infections)ĥ-10mg/kg PO q24h for 7-14d (for pyoderma, to resolution of clinical signs or one week past resolution)įor deep pyoderma, lower respiratory tract infections, or complicated UTIsĥ-20mg/kg PO, IV, or IM q24h for 7-14d (for pyoderma, to resolution of clinical signs or one week past resolution)ĥmg/kg PO q12h treatment may need to continue for up to 8wks in cases of granulomatous colitisĮnrofloxacin is a bactericidal, concentration-dependent fluoroquinolone antibiotic with activity primarily against Gram-negative aerobes, such as Enterobacteriaceae and Pseudomonas aeruginosa.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |